Flex GL

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Flex GL
Generous levels of glucosamine HCl and vitamin C, for focused support of natural lubricants and connective tissues.


Glucosamine: The building block of natural lubricants
The amino sugar glucosamine is an important component of the horse's natural articular lubricants. Glucosamine makes up half of the hyaluronate (hyaluronic acid) molecule, the key to the lubricating properties of the synovial fluid. Glucosamine is readily converted to galactosamine to provide 50 percent of the structure of chondroitin sulfates, as well as keratan and dermatan sulfates. These GAGs combine with proteins and hyaluronate in the cartilage to form the large proteoglycans (PGs) that lubricate and protect the cartilage surface.

Rate-limiting step in GAG production
The production of glucosamine from glucose and glutamine is believed to be the main "rate-limiting step" in the body's production of GAGs. Improved dietary supplies of pre-formed glucosamine help overcome this limitation with natural support. Tests of glucosamine's biochemical properties reveal that it has little direct effect against common inflammatory agents. Instead, glucosamine appears to function as a nutritional precursor, "feeding" the systems that make important GAGs like hyaluronate and chondroitin sulfates. In one test, GAGs in tissues that were deprived of normal glucosamine production returned to normal length within 15 minutes after glucosamine was added. (Clark, Richards, Iozza, Biochem. J., 1991, 273, 283-288)

Vitamin C: Production and Protection
Vitamin C (ascorbic acid) helps in the formation of collagen and GAGs, and also mediates the release of histamine and other pro-inflammatory compounds. Vitamin C also provides broad antioxidant protection against the free radicals that can damage vital tissues. In collagen synthesis, vitamin C serves both to regulate the startup process as well as to "mature" the collagen protein in the final stage of production. Like glucosamine, vitamin C has been shown in laboratory testing to stimulate manufacture of the large proteoglycan (PG) lubricants. Together, glucosamine and vitamin C work to enhance nutritional synergy.

Flex GL Delivers!
Each one ounce serving of Flex GL supplies 5,000 mg quality glucosamine hydrochloride (HCl) plus 5,000 mg pure ascorbic acid. Flex GL is blended with a pleasing, easy-to-feed granulated dextrose base. Glucosamine HCl is a stable, well-absorbed form that is approximately 17% hydrochloride and 83% glucosamine.

Recommended Feeding
Feed 2 to 3 ounces daily for up to 30 days, one ounce daily for maintenance. Serving scoop enclosed.

 

Size Price
4 lb. $ 79.50

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